Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate...
Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
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Author / Creator
Stöcklein, H , Smardova, J , Macak, J , Katzenberger, T , Höller, S , Wessendorf, S , Hutter, G , Dreyling, M , Haralambieva, E , Mäder, U , Müller-Hermelink, H K , Rosenwald, A , Ott, G and Kalla, J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Deletions in the short arm of chromosome 17 (17p) involving the tumor suppressor
TP53
occur in up to 20% of diffuse large B-cell lymphomas (DLBCLs). Although inactivation of both alleles of a tumor suppressor gene is usually required for tumor development, the overlap between
TP53
deletions and mutations is poorly understood in DLBCLs,...
Alternative Titles
Full title
Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
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Record Identifier
TN_cdi_proquest_miscellaneous_69109171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69109171
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1210901
