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Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of fun...

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of fun...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69119732

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

About this item

Full title

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 1998-12, Vol.17 (22), p.2889-2899

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The ATP/ubiquitin-dependent 26S proteasome is a central regulator of cell cycle progression and stress responses. While investigating the application of peptide aldehyde proteasome inhibitors to block signal-induced IkappaBalpha degradation in human LNCaP prostate carcinoma cells, we observed that persistent inhibition of proteasomal activity signa...

Alternative Titles

Full title

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69119732

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69119732

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1202221

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