The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regula...
The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros
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Author / Creator
Greif, P A , Tizazu, B , Krause, A , Kremmer, E and Bohlander, S K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The t(10;11)(p13;q14) translocation leads to the fusion of the CALM and AF10 genes. This translocation can be found as the sole cytogenetic abnormality in acute lymphoblastic leukemia, acute myeloid leukemia and in malignant lymphomas. The expression of CALM/AF10 in primary murine bone marrow cells results in the development of an aggressive leukem...
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Full title
The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_69169263
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69169263
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1210945
