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Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice

Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69232726

Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice

About this item

Full title

Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice

Publisher

New York: Springer-Verlag

Journal title

Calcified tissue international, 2008-05, Vol.82 (5), p.361-372

Language

English

Formats

Publication information

Publisher

New York: Springer-Verlag

More information

Scope and Contents

Contents

Receptor activator for nuclear factor-κ B ligand (RANKL) is an essential mediator of osteoclastogenesis. We hypothesized that administration of soluble RANKL to mice would result in high turnover and deleterious effects on both cortical and trabecular bone. For 10 days, 10-week-old C57BL/6J female mice (
n
 = 12/group) were given twice-daily...

Alternative Titles

Full title

Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69232726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69232726

Other Identifiers

ISSN

0171-967X

E-ISSN

1432-0827

DOI

10.1007/s00223-008-9133-6

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