Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice
Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice
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New York: Springer-Verlag
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English
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New York: Springer-Verlag
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Receptor activator for nuclear factor-κ B ligand (RANKL) is an essential mediator of osteoclastogenesis. We hypothesized that administration of soluble RANKL to mice would result in high turnover and deleterious effects on both cortical and trabecular bone. For 10 days, 10-week-old C57BL/6J female mice (
n
= 12/group) were given twice-daily...
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Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice
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TN_cdi_proquest_miscellaneous_69232726
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69232726
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ISSN
0171-967X
E-ISSN
1432-0827
DOI
10.1007/s00223-008-9133-6