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RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69283622

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

About this item

Full title

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2008-07, Vol.10 (7), p.765-775

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Molecular and cellular mechanisms of epithelial–mesenchymal transition (EMT), crucial in development and pathogenesis, are still poorly understood. Here we provide evidence that distinct cellular steps of EMT occur sequentially during gastrulation. Basement membrane (BM) breakdown is the first recognizable step and is controlled by loss of basally...

Alternative Titles

Full title

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69283622

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69283622

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb1739

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