Crystal structure of the ligand-free G-protein-coupled receptor opsin
Crystal structure of the ligand-free G-protein-coupled receptor opsin
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In the G-protein-coupled receptor (GPCR) rhodopsin, the inactivating ligand 11-
cis
-retinal is bound in the seven-transmembrane helix (TM) bundle and is
cis
/
trans
isomerized by light to form active metarhodopsin II. With metarhodopsin II decay, all-
trans
-retinal is released, and opsin is reloaded with new 11-
cis
...
Alternative Titles
Full title
Crystal structure of the ligand-free G-protein-coupled receptor opsin
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_69312566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69312566
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature07063
