IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
About this item
Full title
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
Author / Creator
Publisher
England
Journal title
Nature (London), 2008-07, Vol.454 (7202), p.350-352
Language
English
Formats
Publication information
Publisher
England
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More information
Scope and Contents
Contents
The recent discovery of CD4(+) T cells characterized by secretion of interleukin (IL)-17 (T(H)17 cells) and the naturally occurring regulatory FOXP3(+) CD4 T cell (nT(reg)) has had a major impact on our understanding of immune processes not readily explained by the T(H)1/T(H)2 paradigm. T(H)17 and nT(reg) cells have been implicated in the pathogene...
Alternative Titles
Full title
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_69318179
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69318179
Other Identifiers
E-ISSN
1476-4687
DOI
10.1038/nature07021
