Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma
Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma
About this item
Full title
Author / Creator
Publisher
Hagerstown, MD: American Association of Neuropathologists, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hagerstown, MD: American Association of Neuropathologists, Inc
Subjects
More information
Scope and Contents
Contents
Primary lymphomas of the CNS (PCNSLs) show molecular features of the late germinal center exit B-cell phenotype and are impaired in their terminal differentiation as indicated by a lack of immunoglobulin class switching. Because the positive regulatory domain I protein with ZNF domain (PRDM1/BLIMP1) is a master regulator of terminal B-cell differen...
Alternative Titles
Full title
Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_69377448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69377448
Other Identifiers
ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1097/NEN.0b013e31817dd02d
