How Drugs Interact with Transporters: SGLT1 as a Model
How Drugs Interact with Transporters: SGLT1 as a Model
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Publisher
New York: New York : Springer-Verlag
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Language
English
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Publisher
New York: New York : Springer-Verlag
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Contents
Drugs are transported by cotransporters with widely different turnover rates. We have examined the underlying mechanism using, as a model system, glucose and indican (indoxyl-β-d-glucopyranoside) transport by human Na⁺/glucose cotransporter (hSGLT1). Indican is transported by hSGLT1 at 10% of the rate for glucose but with a fivefold higher apparent...
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Full title
How Drugs Interact with Transporters: SGLT1 as a Model
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TN_cdi_proquest_miscellaneous_69447877
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69447877
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ISSN
0022-2631
E-ISSN
1432-1424
DOI
10.1007/s00232-008-9116-6
