Orthotopic metastatic mouse models for anticancer drug discovery and evaluation : a bridge to the cl...
Orthotopic metastatic mouse models for anticancer drug discovery and evaluation : a bridge to the clinic
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Publisher
Dordrecht: Kluwer
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Language
English
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Publisher
Dordrecht: Kluwer
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Contents
Currently used rodent tumor models, including transgenic tumor models, or subcutaneously-growing human tumors in immunodeficient mice, do not sufficiently represent clinical cancer, especially with regard to metastasis and drug sensitivity. In order to obtain clinically accurate models, we have developed the technique of surgical orthotopic implant...
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Full title
Orthotopic metastatic mouse models for anticancer drug discovery and evaluation : a bridge to the clinic
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TN_cdi_proquest_miscellaneous_69464592
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69464592
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ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1023/a:1006326203858
