Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel t...
Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics
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Publisher
New York, NY: Elsevier Inc
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Language
English
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Publisher
New York, NY: Elsevier Inc
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Scope and Contents
Contents
In chronic kidney disease, functional impairment correlates with tubulointerstitial fibrosis characterised by inflammation, accumulation of extracellular matrix, tubular atrophy and rarefaction of peritubular capillaries. Loss of the microvasculature implies a hypoxic milieu and suggested an important role for hypoxia when the “chronic hypoxia hypo...
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Full title
Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics
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TN_cdi_proquest_miscellaneous_69548456
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69548456
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2008.350