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Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivative...

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivative...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69588099

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias

About this item

Full title

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Pflügers Archiv, 2008-10, Vol.457 (1), p.223-231

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Glutaric acidurias are rare inherited neurodegenerative disorders accompanied by accumulation of the metabolites glutarate (GA) and 3-hydroxyglutarate (3OHGA), glutaconate,
L
-, or
D
-2-hydroxyglutarate (
L
-2OHGA,
D
-2OHGA) in all body fluids. Oocytes expressing the human (h) sodium-dicarboxylate cotransporter (NaDC3) showe...

Alternative Titles

Full title

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69588099

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69588099

Other Identifiers

ISSN

0031-6768

E-ISSN

1432-2013

DOI

10.1007/s00424-008-0489-2

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