MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
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Author / Creator
Fornari, F , Gramantieri, L , Ferracin, M , Veronese, A , Sabbioni, S , Calin, G A , Grazi, G L , Giovannini, C , Croce, C M , Bolondi, L and Negrini, M
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The identification of target mRNAs is a key step for assessing the role of aberrantly expressed microRNAs in human cancer. MiR-221 is upregulated in human hepatocellular carcinoma (HCC) as well as in other malignancies. One proven target of miR-221 is CDKN1B/p27, whose downregulation affects HCC prognosis. Here, we proved that the cyclin-dependent...
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Full title
MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
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TN_cdi_proquest_miscellaneous_69600093
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69600093
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2008.178
