Preclinical discovery of ixabepilone, a highly active antineoplastic agent
Preclinical discovery of ixabepilone, a highly active antineoplastic agent
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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More information
Scope and Contents
Contents
The epothilones and their analogs constitute a novel class of antineoplastic agents, produced by the myxobacterium
Sorangium cellulosum
. These antimicrotubule agents act in a similar manner to taxanes, stabilizing microtubules and resulting in arrested tumor cell division and apoptosis. Unlike taxanes, however, epothilones and their analogs...
Alternative Titles
Full title
Preclinical discovery of ixabepilone, a highly active antineoplastic agent
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Record Identifier
TN_cdi_proquest_miscellaneous_69620619
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69620619
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-008-0724-8
