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Accumulation of HtrA2/Omi in Neuronal and Glial Inclusions in Brains With α-Synucleinopathies

Accumulation of HtrA2/Omi in Neuronal and Glial Inclusions in Brains With α-Synucleinopathies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69624913

Accumulation of HtrA2/Omi in Neuronal and Glial Inclusions in Brains With α-Synucleinopathies

About this item

Full title

Accumulation of HtrA2/Omi in Neuronal and Glial Inclusions in Brains With α-Synucleinopathies

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

Journal title

Journal of neuropathology and experimental neurology, 2008-10, Vol.67 (10), p.984-993

Language

English

Formats

Publication information

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

More information

Scope and Contents

Contents

HtrA2/Omi is a mitochondrial serine protease that is released into the cytosol and promotes apoptotic processes by binding to several members of the inhibitors of apoptosis protein family. HtrA2/Omi knockout mice show a parkinsonian phenotype, and mutations in the gene encoding HtrA2/Omi have been identified as susceptibility factors for Parkinson...

Alternative Titles

Full title

Accumulation of HtrA2/Omi in Neuronal and Glial Inclusions in Brains With α-Synucleinopathies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69624913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69624913

Other Identifiers

ISSN

0022-3069

E-ISSN

1554-6578

DOI

10.1097/NEN.0b013e31818809f4

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