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Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69648784

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

About this item

Full title

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Human genetics, 2008-10, Vol.124 (3), p.271-278

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Although the association of germline
BRCA2
mutations with pancreatic adenocarcinoma is well established, the role of
BRCA1
mutations is less clear. We hypothesized that the loss of heterozygosity at the
BRCA1
locus occurs in pancreatic cancers of germline
BRCA1
mutation carriers, acting as a “second-hit” event contributing t...

Alternative Titles

Full title

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69648784

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69648784

Other Identifiers

ISSN

0340-6717

E-ISSN

1432-1203

DOI

10.1007/s00439-008-0554-0

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