Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins
Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins
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Publisher
Boston: Boston : Springer US
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Language
English
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Publisher
Boston: Boston : Springer US
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Contents
Alteration of glycoprotein glycans often changes various properties of the glycoprotein. To understand the significance of N-glycosylation in the pathogenesis of early-onset familial Alzheimer's disease (AD) and in β-amyloid (Aβ) production, we examined whether the mutations in the amyloid precursor protein (APP) gene found in familial AD affect th...
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Full title
Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins
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TN_cdi_proquest_miscellaneous_69662336
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69662336
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ISSN
0282-0080
E-ISSN
1573-4986
DOI
10.1007/s10719-008-9140-x
