Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Frontotemporal dementia (FTD) is characterized by cognitive and behavioral changes and, in a significant subset of patients, Parkinsonism. Histopathologically, FTD frequently presents with tau-containing lesions, which in familial cases result from mutations in the MAPT gene encoding tau. Here we present a novel transgenic mouse strain (K3) that ex...
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Full title
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
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TN_cdi_proquest_miscellaneous_69674650
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69674650
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0808084105