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Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69674650

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

About this item

Full title

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (41), p.15997-16002

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Frontotemporal dementia (FTD) is characterized by cognitive and behavioral changes and, in a significant subset of patients, Parkinsonism. Histopathologically, FTD frequently presents with tau-containing lesions, which in familial cases result from mutations in the MAPT gene encoding tau. Here we present a novel transgenic mouse strain (K3) that ex...

Alternative Titles

Full title

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69674650

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69674650

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0808084105

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