Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 rec...
Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Interleukin 4 (IL-4) drives T helper type 2 differentiation, whereas IL-2 augments
Il4
chromatin accessibility. Leonard and colleagues now find that IL-2 also maintains the expression of
Il4ra
and other genes in T helper type 2–committed cells.
T helper type 2 (T
H
2) cells are essential for humoral immunity and host defense. I...
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Full title
Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression
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TN_cdi_proquest_miscellaneous_69686605
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69686605
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1656