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Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 rec...

Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 rec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69686605

Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression

About this item

Full title

Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2008-11, Vol.9 (11), p.1288-1296

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Interleukin 4 (IL-4) drives T helper type 2 differentiation, whereas IL-2 augments
Il4
chromatin accessibility. Leonard and colleagues now find that IL-2 also maintains the expression of
Il4ra
and other genes in T helper type 2–committed cells.
T helper type 2 (T
H
2) cells are essential for humoral immunity and host defense. I...

Alternative Titles

Full title

Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69686605

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69686605

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.1656

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