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The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69767603

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

About this item

Full title

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2008-11, Vol.14 (11), p.1271-1277

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Two microRNAs, miR-15a and miR-16, localize to a chromosome region that is frequently deleted in cancer. Bonci
et al
. now show that these microRNAs have tumor suppressive effects in prostate cancer cells and regulate the expression of crucial oncogenic targets.
MicroRNAs (miRNAs) are noncoding small RNAs that repress protein translation b...

Alternative Titles

Full title

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69767603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69767603

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.1880

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