A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
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Cadwell, Ken , Liu, John Y. , Brown, Sarah L. , Miyoshi, Hiroyuki , Loh, Joy , Lennerz, Jochen K. , Kishi, Chieko , Kc, Wumesh , Carrero, Javier A. , Hunt, Steven , Stone, Christian D. , Brunt, Elizabeth M. , Xavier, Ramnik J. , Sleckman, Barry P. , Li, Ellen , Mizushima, Noboru , Stappenbeck, Thaddeus S. and Virgin IV, Herbert W.
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Inflammatory bowel disease
Crohn's disease, a chronic inflammation of the gut, has been linked to over thirty gene loci. Two papers in this issue focus a recent addition to that list, ATG16L1 (Atg16-like 1). Atg16 protein itself was first identified in yeast as an essential gene for the process of autophagy, a system that clears away unwanted ce...
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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
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TN_cdi_proquest_miscellaneous_69777435
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69777435
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature07416
