LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions
LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Certain genetic defects in LRRK2 and parkin are pathogenic for Parkinson’s disease (PD) and both proteins deposit in the characteristic Lewy bodies. LRRK2 is thought to be involved in the early initiation of Lewy bodies. The involvement of LRRK2 and parkin in the similar cellular deposition of fibrillar α-synuclein in glial cytoplasmic inclusions (...
Alternative Titles
Full title
LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_69803170
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69803170
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-008-0446-3
