The genetics of the p53 pathway, apoptosis and cancer therapy
The genetics of the p53 pathway, apoptosis and cancer therapy
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The p53 tumour suppressor pathway is an attractive target for the development of anticancer therapies. This Perspective highlights recent progress with agents that modulate components of the p53 pathway — in particular, p53 itself and its negative regulator MDM2 — focusing on how studies of their genetic variations, including mutations in cancer ce...
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Full title
The genetics of the p53 pathway, apoptosis and cancer therapy
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TN_cdi_proquest_miscellaneous_69848413
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69848413
Other Identifiers
ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd2656
