Sox18 induces development of the lymphatic vasculature in mice
Sox18 induces development of the lymphatic vasculature in mice
About this item
Full title
Author / Creator
François, Mathias , Caprini, Andrea , Hosking, Brett , Orsenigo, Fabrizio , Wilhelm, Dagmar , Browne, Catherine , Paavonen, Karri , Karnezis, Tara , Shayan, Ramin , Downes, Meredith , Davidson, Tara , Tutt, Desmond , Cheah, Kathryn S. E. , Stacker, Steven A. , Muscat, George E. O. , Achen, Marc G. , Dejana, Elisabetta and Koopman, Peter
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Sox18 as a lymphatic switch
Mutations in the Sox18 transcription factor gene cause lymphatic dysfunction in the rare human syndrome hypotrichosis-lymphoedema-telangiectasia, suggesting that it may play a role in lymphatic development of function. That role has now been identified: Sox18 acts as a molecular switch to induce differentiation of lym...
Alternative Titles
Full title
Sox18 induces development of the lymphatic vasculature in mice
Authors, Artists and Contributors
Author / Creator
Caprini, Andrea
Hosking, Brett
Orsenigo, Fabrizio
Wilhelm, Dagmar
Browne, Catherine
Paavonen, Karri
Karnezis, Tara
Shayan, Ramin
Downes, Meredith
Davidson, Tara
Tutt, Desmond
Cheah, Kathryn S. E.
Stacker, Steven A.
Muscat, George E. O.
Achen, Marc G.
Dejana, Elisabetta
Koopman, Peter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_69863422
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69863422
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature07391
