Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis
Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis
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Author / Creator
Webb, C P , Taylor, G A , Jeffers, M , Fiscella, M , Oskarsson, M , Resau, J H and Woude, GF Vande
Publisher
Basingstoke: Nature Publishing
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Language
English
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Publisher
Basingstoke: Nature Publishing
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Scope and Contents
Contents
Aberrations in Met-hepatocyte growth factor/scatter factor (HGF/SF) signaling have been implicated in the acquisition of tumorigenic and metastatic phenotypes. Here we show that murine NIH3T3 and C127 cells transformed by the Ras oncogene overexpress the Met receptor, resulting in enhanced HGF/SF-mediated responses in vitro including invasion throu...
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Full title
Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis
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Record Identifier
TN_cdi_proquest_miscellaneous_70025500
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70025500
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1202135