3-Nitropropionic Acid (3-NPA) Produces Hypothermia and Inhibits Histochemical Labeling of Succinate...
3-Nitropropionic Acid (3-NPA) Produces Hypothermia and Inhibits Histochemical Labeling of Succinate Dehydrogenase (SDH) in Rat Brain
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Full title
Author / Creator
Nony, P.A. , Scallet, A.C. , Rountree, R.L. , Ye, X. and Binienda, Z.
Publisher
New York, NY: Springer
Journal title
Language
English
Formats
Publication information
Publisher
New York, NY: Springer
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Scope and Contents
Contents
3-Nitropropionic acid (3-NPA) is a toxin sometimes produced on moldy crops (sugarcane, peanuts, etc.) in amounts sufficient to cause severe neurological disorders when consumed by humans. In vitro, 3-NPA irreversibly inactivates SDH, a Complex II respiratory enzyme required for mitochondrial energy production. A single dose of 3-NPA (30 mg/kg s.c.)...
Alternative Titles
Full title
3-Nitropropionic Acid (3-NPA) Produces Hypothermia and Inhibits Histochemical Labeling of Succinate Dehydrogenase (SDH) in Rat Brain
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70041221
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70041221
Other Identifiers
ISSN
0885-7490
E-ISSN
1573-7365
DOI
10.1023/A:1020753629477
