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Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic...

Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70071552

Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic Behavior of the S1 Binding Pocket

About this item

Full title

Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic Behavior of the S1 Binding Pocket

Publisher

United Arab Emirates: Bentham Science Publishers Ltd

Journal title

Current pharmaceutical design, 2007-12, Vol.13 (34), p.3471-3475

Language

English

Formats

Publication information

Publisher

United Arab Emirates: Bentham Science Publishers Ltd

More information

Scope and Contents

Contents

Matrix Metalloproteinases (MMPs) are zinc-containing proteinases that are responsible for the metabolism of extracellular matrix proteins. Overexpression of MMPs has been associated with a wide range of pathological diseases such as arthritis, cancer, multiple sclerosis and Alzheimers disease. The excessive and unregulated activity of Matrix Metall...

Alternative Titles

Full title

Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic Behavior of the S1 Binding Pocket

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70071552

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70071552

Other Identifiers

ISSN

1381-6128

E-ISSN

1873-4286

DOI

10.2174/138161207782794211

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