Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5
Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5
About this item
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Author / Creator
Martin, Maureen P. , Dean, Michael , Smith, Michael W. , Winkler, Cheryl , Gerrard, Bernard , Michael, Nelson L. , Lee, Benhur , Doms, Robert W. , Margolick, Joseph , Buchbinder, Susan , Goedert, James J. , O'Brien, Thomas R. , Hilgartner, Margaret W. , Vlahov, David , O'Brien, Stephen J. and Carrington, Mary
Publisher
Washington, DC: American Society for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Scope and Contents
Contents
The CCR5 gene encodes a cell surface chemokine receptor molecule that serves as the principal coreceptor, with CD4, for macrophage-tropic (R5) strains of human immunodeficiency virus-type 1 (HIV-1). Genetic association analysis of five cohorts of people with acquired immunodeficiency syndrome (AIDS) revealed that infected individuals homozygous for...
Alternative Titles
Full title
Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5
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Record Identifier
TN_cdi_proquest_miscellaneous_70094724
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70094724
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.282.5395.1907
