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Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70191364

Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

About this item

Full title

Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2008-01, Vol.319 (5860), p.195-198

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Angiogenesis-mediated progression of micrometastasis to lethal macrometastasis is the major cause of death in cancer patients. Here, using mouse models of pulmonary metastasis, we identify bone marrow (BM)-derived endothelial progenitor cells (EPCs) as critical regulators of this angiogenic switch. We show that tumors induce expression of the trans...

Alternative Titles

Full title

Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70191364

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70191364

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1150224

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