Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis
Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Angiogenesis-mediated progression of micrometastasis to lethal macrometastasis is the major cause of death in cancer patients. Here, using mouse models of pulmonary metastasis, we identify bone marrow (BM)-derived endothelial progenitor cells (EPCs) as critical regulators of this angiogenic switch. We show that tumors induce expression of the trans...
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Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis
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TN_cdi_proquest_miscellaneous_70191364
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70191364
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1150224