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Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70248912

Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

About this item

Full title

Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

Publisher

Schiphol: Bentham Science Publishers Ltd

Journal title

Current medicinal chemistry, 2007-02, Vol.14 (5), p.601-623

Language

English

Formats

Publication information

Publisher

Schiphol: Bentham Science Publishers Ltd

More information

Scope and Contents

Contents

Aberrant signaling caused by mutations in the RAS-RAF-MEK-ERK pathway and its upstream activators critically contributes to human tumor development. Strategies, which aim at inhibiting hyperactive signaling molecules, appear conceptually straight forward, but their translation into clinical practice has been hampered by many setbacks. Understanding...

Alternative Titles

Full title

Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70248912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70248912

Other Identifiers

ISSN

0929-8673

E-ISSN

1875-533X

DOI

10.2174/092986707780059670

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