The mitochondrial serine protease HtrA2/Omi: an overview
The mitochondrial serine protease HtrA2/Omi: an overview
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The HtrA family refers to a group of related oligomeric serine proteases that combine a trypsin-like protease domain with at least one PDZ interaction domain. Mammals encode four HtrA proteases, named HtrA1–4. The protease activity of the HtrA member HtrA2/Omi is required for mitochondrial homeostasis in mice and humans and inactivating mutations a...
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Full title
The mitochondrial serine protease HtrA2/Omi: an overview
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TN_cdi_proquest_miscellaneous_70297155
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70297155
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/sj.cdd.4402291
