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Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apol...

Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apol...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70299303

Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apolipoprotein A-I

About this item

Full title

Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apolipoprotein A-I

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Naunyn-Schmiedeberg's archives of pharmacology, 2008-03, Vol.377 (1), p.35-43

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Double heterozygous mice lacking
Apoa1
and
Cbs
genes show mild hyperhomocysteinemia in combination with hypoalphalipoproteinemia. This situation leads to a moderate hypertension associated with a dysregulation in nitric oxide metabolism. The aim of this study was to investigate the potential beneficial effects of statin treatment in the...

Alternative Titles

Full title

Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apolipoprotein A-I

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70299303

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70299303

Other Identifiers

ISSN

0028-1298

E-ISSN

1432-1912

DOI

10.1007/s00210-007-0247-6

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