The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL...
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone
About this item
Full title
Author / Creator
Beattie, D T , Cheruvu, M , Mai, N , O'Keefe, M , Johnson-Rabidoux, S , Peterson, C , Kaufman, E and Vickery, R
Publisher
Germany
Journal title
Language
English
Formats
Publication information
Publisher
Germany
Subjects
More information
Scope and Contents
Contents
This study characterized the pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, its metabolite, ADL 08-0011, and methylnaltrexone. The activities of the compounds were investigated with respect to human or guinea pig opioid receptor binding and function in recombinant cell lines and mechanical responsiveness of the...
Alternative Titles
Full title
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70320830
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70320830
Other Identifiers
ISSN
0028-1298
E-ISSN
1432-1912
DOI
10.1007/s00210-007-0146-x
