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Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin wi...

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin wi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70371320

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2

About this item

Full title

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2008-03, Vol.15 (3), p.280-287

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Ubiquitin-like proteins (UBLs) modify targets via related E1-E2-E3 cascades. How is UBL conjugation fidelity established? Here we report the basis for UBL selection by UBL conjugating enzyme 12 (Ubc12), which is specific for the neural precursor cell expressed, developmentally down-regulated protein 8 (NEDD8), and does not form a thioester-linked c...

Alternative Titles

Full title

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70371320

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70371320

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.1387

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