Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin wi...
Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Ubiquitin-like proteins (UBLs) modify targets via related E1-E2-E3 cascades. How is UBL conjugation fidelity established? Here we report the basis for UBL selection by UBL conjugating enzyme 12 (Ubc12), which is specific for the neural precursor cell expressed, developmentally down-regulated protein 8 (NEDD8), and does not form a thioester-linked c...
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Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2
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TN_cdi_proquest_miscellaneous_70371320
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70371320
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1545-9993
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1545-9985
DOI
10.1038/nsmb.1387