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Kindlin-3 is essential for integrin activation and platelet aggregation

Kindlin-3 is essential for integrin activation and platelet aggregation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70373922

Kindlin-3 is essential for integrin activation and platelet aggregation

About this item

Full title

Kindlin-3 is essential for integrin activation and platelet aggregation

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2008-03, Vol.14 (3), p.325-330

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Integrin-mediated platelet adhesion and aggregation are essential for sealing injured blood vessels and preventing blood loss, and excessive platelet aggregation can initiate arterial thrombosis, causing heart attacks and stroke
1
. To ensure that platelets aggregate only at injury sites, integrins on circulating platelets exist in a low-affi...

Alternative Titles

Full title

Kindlin-3 is essential for integrin activation and platelet aggregation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70373922

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70373922

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1722

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