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Human Epidermal Keratinocytes Accumulate Superoxide Due to Low Activity of Mn-SOD, Leading to Mitoch...

Human Epidermal Keratinocytes Accumulate Superoxide Due to Low Activity of Mn-SOD, Leading to Mitoch...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70381276

Human Epidermal Keratinocytes Accumulate Superoxide Due to Low Activity of Mn-SOD, Leading to Mitochondrial Functional Impairment

About this item

Full title

Human Epidermal Keratinocytes Accumulate Superoxide Due to Low Activity of Mn-SOD, Leading to Mitochondrial Functional Impairment

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2007-05, Vol.127 (5), p.1084-1093

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

The energy metabolism of the epidermis has been the subject of controversy; thus we characterized the mitochondrial phenotype of human primary keratinocytes and fibroblasts, in cell culture and in human skin sections. We found that keratinocytes respire as much as fibroblasts, however, maximal activities of the respiratory chain (RC) complexes were...

Alternative Titles

Full title

Human Epidermal Keratinocytes Accumulate Superoxide Due to Low Activity of Mn-SOD, Leading to Mitochondrial Functional Impairment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70381276

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70381276

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/sj.jid.5700666

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