Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons
Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In postmitotic sympathetic neurons, unlike most mitotic cells, death by apoptosis requires not only the release of cytochrome
c
from the mitochondria, but also an additional step to relieve X-linked inhibitor of apoptosis protein (XIAP)'s inhibition of caspases. Here, we examined the mechanism by which XIAP is inactivated following DNA damage...
Alternative Titles
Full title
Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70392355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70392355
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/sj.cdd.4402084
