Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons
Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons
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Full title
Author / Creator
Komatsu, M , Ueno, T , Waguri, S , Uchiyama, Y , Kominami, E and Tanaka, K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Investigations pursued during the last decade on neurodegenerative diseases have revealed a common mechanism underlying the development of such diseases: conformational disorder of certain proteins leads to the formation of misfolded protein oligomers, which subsequently develop into large protein aggregates. These aggregates entangle other denatur...
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Full title
Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons
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Record Identifier
TN_cdi_proquest_miscellaneous_70396471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70396471
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/sj.cdd.4402120