An optimized lentivirus-mediated RNAi screen reveals kinase modulators of kinesin-5 inhibitor sensit...
An optimized lentivirus-mediated RNAi screen reveals kinase modulators of kinesin-5 inhibitor sensitivity
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Author / Creator
Publisher
United States: Mary Ann Liebert, Inc
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Language
English
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Publisher
United States: Mary Ann Liebert, Inc
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Contents
Induction of RNA interference (RNAi) in human cells has enabled comprehensive functional annotation of the human genome via reverse genetic screens. Here we describe an optimized semiautomated method to produce, titrate, and screen large collections of short hairpin RNA (shRNA)-containing lentiviral vectors. We also present results from a pilot len...
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Full title
An optimized lentivirus-mediated RNAi screen reveals kinase modulators of kinesin-5 inhibitor sensitivity
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Record Identifier
TN_cdi_proquest_miscellaneous_70402911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70402911
Other Identifiers
ISSN
1540-658X
E-ISSN
1557-8127
DOI
10.1089/adt.2007.106
