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The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70476412

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

About this item

Full title

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2008-04, Vol.15 (4), p.373-380

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The retinitis pigmentosa 2 (RP2) gene is responsible for a particular variant of X chromosome–linked eye disease. Previously, RP2 was shown to bind the GTP form of the small G protein Arf-like 3 (Arl3), thus qualifying as an effector. Here we present the Arl3–GppNHp–RP2 complex structure, which shows features resembling complexes with GTPase-activa...

Alternative Titles

Full title

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70476412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70476412

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.1396

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