Reducing Endogenous Tau Ameliorates Amyloid β-Induced Deficits in an Alzheimer's Disease Mouse Model
Reducing Endogenous Tau Ameliorates Amyloid β-Induced Deficits in an Alzheimer's Disease Mouse Model
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
Many potential treatments for Alzheimer's disease target amyloid-β peptides (Aβ), which are widely presumed to cause the disease. The microtubule-associated protein tau is also involved in the disease, but it is unclear whether treatments aimed at tau could block Aβ-induced cognitive impairments. Here, we found that reducing endogenous tau levels p...
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Full title
Reducing Endogenous Tau Ameliorates Amyloid β-Induced Deficits in an Alzheimer's Disease Mouse Model
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TN_cdi_proquest_miscellaneous_70479074
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70479074
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1141736
