Mammalian RNA polymerase II core promoters: insights from genome-wide studies
Mammalian RNA polymerase II core promoters: insights from genome-wide studies
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Genome-wide methods have identified fivefold to tenfold more transcription start sites (TSSs) than were previously known to exist. Many of these occur at unexpected locations, such as assumed gene deserts, exons and 3′ UTRs of known genes.
Most promoters are not represented by the accepted model of a single TSS with an upstream TAT...
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Full title
Mammalian RNA polymerase II core promoters: insights from genome-wide studies
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TN_cdi_proquest_miscellaneous_70515228
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70515228
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ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/nrg2026
