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FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70573564

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

About this item

Full title

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2007-06, Vol.14 (6), p.564-567

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Activation of the Fanconi anemia (FA) DNA damage–response pathway results in the monoubiquitination of FANCD2, which is regulated by the nuclear FA core ubiquitin ligase complex. A FANCD2 protein sequence–based homology search facilitated the discovery of FANCI, a second monoubiquitinated component of the FA pathway. Biallelic mutations in the gene...

Alternative Titles

Full title

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70573564

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70573564

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb1252

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