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High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-depen...

High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-depen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70678798

High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases

About this item

Full title

High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases

Publisher

United States: American Society for Investigative Pathology

Journal title

The American journal of pathology, 2001-03, Vol.158 (3), p.1091-1100

Language

English

Formats

Publication information

Publisher

United States: American Society for Investigative Pathology

More information

Scope and Contents

Contents

Hypertrophy of mesangial cells is one of the earliest morphological alterations in the kidney after the onset of diabetes mellitus. We have previously shown that cultured mesangial cells exposed to high ambient glucose arrest in the G1 phase of the cell cycle and that this is associated with an increased expression of inhibitors of the cyclin-depen...

Alternative Titles

Full title

High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70678798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70678798

Other Identifiers

ISSN

0002-9440

E-ISSN

1525-2191

DOI

10.1016/S0002-9440(10)64056-4

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