Targeting XIAP for the treatment of malignancy
Targeting XIAP for the treatment of malignancy
About this item
Full title
Author / Creator
Schimmer, A D , Dalili, S , Batey, R A and Riedl, S J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
X-linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis proteins family of caspase inhibitors that selectively binds and inhibits caspases-3, -7 and -9, but not caspase-8. As such, XIAP blocks a substantial portion of the apoptosis pathway and is an attractive target for novel therapeutic agents for the treatment of...
Alternative Titles
Full title
Targeting XIAP for the treatment of malignancy
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70681865
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70681865
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/sj.cdd.4401826
