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Determination of drug-serum protein interactions via fluorescence polarization measurements

Determination of drug-serum protein interactions via fluorescence polarization measurements

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70682994

Determination of drug-serum protein interactions via fluorescence polarization measurements

About this item

Full title

Determination of drug-serum protein interactions via fluorescence polarization measurements

Author / Creator

Publisher

Germany: Berlin/Heidelberg : Springer-Verlag

Journal title

Analytical and bioanalytical chemistry, 2007-07, Vol.388 (5-6), p.1147-1156

Language

English

Formats

Publication information

Publisher

Germany: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

New fast methods for the determination of pharmacokinetic behaviour of potential drug candidates are receiving increasing interest. We present a new homogeneous method for the determination of drug binding and drug competition for human serum albumin and α₁-acid glycoprotein that is amenable to high-throughput-screening. It is based on selective fl...

Alternative Titles

Full title

Determination of drug-serum protein interactions via fluorescence polarization measurements

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70682994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70682994

Other Identifiers

ISSN

1618-2642

E-ISSN

1618-2650

DOI

10.1007/s00216-007-1351-7

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