Ryanodine Receptor/Calcium Release Channel PKA Phosphorylation: A Critical Mediator of Heart Failure...
Ryanodine Receptor/Calcium Release Channel PKA Phosphorylation: A Critical Mediator of Heart Failure Progression
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Defective regulation of the cardiac ryanodine receptor (RyR2)/calcium release channel, required for excitation-contraction coupling in the heart, has been linked to cardiac arrhythmias and heart failure. For example, diastolic calcium "leak" via RyR2 channels in the sarcoplasmic reticulum has been identified as an important factor contributing to i...
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Full title
Ryanodine Receptor/Calcium Release Channel PKA Phosphorylation: A Critical Mediator of Heart Failure Progression
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TN_cdi_proquest_miscellaneous_70693361
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70693361
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0510113103
