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Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70699431

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas

About this item

Full title

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas

Publisher

Berlin: Springer

Journal title

Journal of molecular medicine (Berlin, Germany), 2006-01, Vol.84 (1), p.37-45

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

Mammalian inner ear hair cells in cochleas are believed to be incapable of regeneration after birth, which hampers treatment of sensorineural hearing impairment mainly caused by hair cell loss. Sensory epithelia of cochleas are composed of hair cells and supporting cells, both of which originate from common progenitors. Notch/RBP-J signaling is an...

Alternative Titles

Full title

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70699431

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70699431

Other Identifiers

ISSN

0946-2716

E-ISSN

1432-1440

DOI

10.1007/s00109-005-0706-9

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