Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Defects in dendritic spines are common to several forms of cognitive deficits, including mental retardation and Alzheimer disease. Because mutation of p21-activated kinase (PAK) can lead to mental retardation and because PAK-cofilin signaling is critical in dendritic spine morphogenesis and actin dynamics, we hypothesized that the PAK pathway is in...
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Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
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TN_cdi_proquest_miscellaneous_70709823
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70709823
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1630
