Vascular normalization in Rgs5-deficient tumours promotes immune destruction
Vascular normalization in Rgs5-deficient tumours promotes immune destruction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Anticancer immunotherapy: It's in the blood
RGS5, a signalling protein that regulates the activity of G proteins, is shown to be an important regulator of the tumour vasculature. Deletion of
Rgs5
leads to normalization of blood vessels of tumours, making them less leaky and improving their coverage with pericytes. As a consequence, more im...
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Full title
Vascular normalization in Rgs5-deficient tumours promotes immune destruction
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TN_cdi_proquest_miscellaneous_70724596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70724596
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature06868
